Pharmaceutical formulas containing the compound sildenafil are potent vasodilators. Sildenafil is used to treat erectile dysfunction in men, as well as normalize the natural response to sexual stimulation.
The first drug containing as an active ingredient the sildenafil was the famous Viagra. In principle, Viagra is available yet, but the initial cost of the tablet in two to four times higher than that of its generic. Any preparation, comprising as the active ingredient, sildenafil, will have the same therapeutic effect. These medicines in the pharmaceutical market are so-called generic. There are many medications with this active ingredient. In addition, they contain the same amount of this active substance. These products are manufactured by different pharmaceutical companies under different names: Viagra, Pfiagra, Kamagra, Revacio, Sildenafil, Sul digra, Suhagra, Edegra etc
Sildenafil is a selective inhibitor of the Cgmp-phosphodiesterase type 5 (PDE-5), an agent vasodilator. It is an oral medication for the treatment of erectile dysfunction and the failure of the response in the genital; it restores erectile function is deficient and provides a natural response to sexual stimulation. In patients with pulmonary arterial hypertension; it also considerably reduces the pressure in the pulmonary artery, improves quality of life. It is used to treat erectile dysfunction (organic, psychogenic, mixed), and pulmonary hypertension.
Sildenafil is taken orally, approximately 1 hour before sexual intercourse at a dose of 50 mg. Given the tolerance and effectiveness, dose may be reduced to 25 mg or increased to 100 mg. The maximum daily dose is 100 mg, the maximum frequency of admission recommended - once a day.
For patients older than 65 years of age and with renal failure, concomitant or hepatic impairment, the dose is 25 mg. After oral administration, sildenafil is rapidly absorbed. Sildenafil in combination with fatty foods reduces the absorption rate.
The side effects:
In case of an overdose of sildenafil increased side effects. It is necessary to perform a symptomatic treatment, the hemodialysis is ineffective.
Interactions with other drugs:
Precautions: before taking sildenafil, it is necessary to undertake a survey of the cardiovascular system. Must be cautious patients with anatomical deformation of the penis and people with diseases that predispose to the development of priapism. Should not be used in patients for whom sexual activity is not desirable.